A rationally designed vaccine for tuberculosis (Old ID 26852)

Role

Collaborator

Description

Tuberculosis kills more people than any other infectious disease, and approximately one third of the world's population is latently infected with Mycobacterium tuberculosis. Reactivation of latent tuberculosis is associated with immunosuppressive conditions, most notably AIDS and type 2 diabetes. This project aims to investigate correlates of protection against tuberculosis in these immunosuppressive conditions by using innovative mouse models and human samples and to develop a new TB vaccine.

Date

01 Jan 2021 - 31 Dec 2025

Project Type

GRANT

Keywords

Mycobacterium tuberculosis;AIDS;Bcg;Vaccination;Type 2 Diabetes

Funding Body

N/A

Amount

0

Project Team

Denise Doolan;Matt Field;Emma McBryde